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Frontiers | Emergence of Dengue 4 as Dominant Serotype During 2017 Outbreak in South India and Associated Cytokine Expression Profile

Dengue virus infection is prevalent in tropical and sub-tropical regions of the world, which is fatal if untreated symptomatically. Emergence of new genotype within serotypes led to enhanced severity. The objective of the study is to identify the molecular characteristics of the DENV circulated during 2017 outbreak in Tamil Nadu, India and, to investigate the role of inflammatory cytokines in different ‘serotypes’ and in ‘dengue severity’. A total of 135 suspected samples were tested for DENV infection using IgM, IgG and qPCR assay; where 76 samples were positive for DENV and analysed for twelve inflammatory cytokines using ELISA. Serotyping shows 14 DENV-1, 22 DENV-2, 7 DENV-3 and 33 DENV-4, where DENV-4 was predominant. Among seventy-six, forty-two isolates were successfully sequenced for C-prM region and grouped. A lineage shift was observed in DENV-4 genotype. Irrespective of serotypes, IFNγ was significantly elevated than control and in primary infection indicating its ro ....

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If You Live in These States, Prepare for More of This Deadly Spider, Experts Say

If You Live in These States, Prepare for More of This Deadly Spider, Experts Say
msn.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from msn.com Daily Mail and Mail on Sunday newspapers.

United States , Jay Everitt , Rottler Pest Solutions , Medical Entomology , ஒன்றுபட்டது மாநிலங்களில் , மிச Ou ரி , ஜெய் எவரிட் , ரோட்லர் பூச்சி தீர்வுகள் , மருத்துவ பூச்சியியல் ,

Moustiques : Voici pourquoi certaines personnes se font plus piquer que d'autres

Moustiques : Voici pourquoi certaines personnes se font plus piquer que d'autres
cnews.fr - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from cnews.fr Daily Mail and Mail on Sunday newspapers.

Medical Entomology , மருத்துவ பூச்சியியல் ,