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Cleveland Clinic receives $6.7 million NIH grant to study high-intensity exercise as Alzheimer s prevention Contributed photo With the support of a $6.7 million NIH grant, Cleveland Clinic researchers will evaluate whether high-intensity exercise can prevent the development of Alzheimer’s disease. Cleveland Clinic has received a $6.7 million grant for a five-year study assessing the effect of home-based indoor cycling in slowing disease progression in healthy older people at high genetic risk for developing Alzheimer s disease, according to a news release. The grant, from the National Institutes of Health, supports a randomized control trial exploring whether a long-term exercise intervention program can alter progression of late-onset Alzheimer s disease in sedentary, high-risk individuals. If successful, the trial has the potential to provide a scalable, low-cost intervention that could substantially reduce health care costs by modifying the disease trajectory. ....