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Uncovering the Anti-Myeloma Resistance Files


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Multiple myeloma (a type of blood cancer) patients live much longer today than in the past, thanks to new targeted anti-myeloma drugs, but ultimately most develop resistance to the medications, and in some the disease is resistant to therapy from the start. Weizmann Institute of Science researchers, in collaboration with physicians from 
Tel Aviv Sourasky Medical Center (TASMC), have made use of extremely sensitive genomic technology to reveal genetic pathways that characterize some of the more resistant cases of multiple myeloma. 
Nature Medicine, may lead to a more informed, personalized treatment for these patients, and it paves the way to using this new technology for discovering additional disease targets in other cancers. ....

Mouna Ballan , Tamar Tadmor , Yaelc Cohen , Gadi Moshe , Oren Pasvolsky , Chezi Ganzel , Meirav Laiba , Chamutal Bornstein , Baoguo Li , Eyal David , Jacqui Scheinberg , Ido Amit , Assaf Weiner , Osnat Jarchowcky Dolberg , Efrat Luttwak , Noa Lavi , Mor Zada , Irit Avivi , Olga Shvetz , Chamutal Gur , Evgeni Chubar , Iuliana Vaxman , Ofer Shpilberg , Anatoly Nemets , Anita James Rosen Foundation , Moross Integrated Cancer Center ,

One dose of COVID-19 vaccine provokes strong immune response in those previously infected


Oxford University to test Covid-19 vaccine response in children
Although clinical trial data are encouraging, real-world evidence with regard to the COVID-19 vaccine remains scarce. In particular, response to the vaccine among those previously infected with SARS-CoV-2 is still not completely understood.
Researchers from Bar-Ilan University and Ziv Medical Center now report preliminary evidence that people previously infected with the virus responded very strongly to one dose of the Pfizer vaccine, regardless of when they were infected and whether or not they had detectable antibodies against COVID-19 prior to receiving the vaccine.
Their study, published in the journal
Eurosurveillance, was conducted on a cohort of 514 staff members at Ziv Medical Center. Seventeen of them were infected with COVID-19 anytime between one and ten months before receiving the first dose of the vaccine. Antibody levels of the entire cohort were measured prior to vaccination and thereaf ....

Michael Edelstein , Ziv Medical Center , Ilan University , Oxford University , Bar Ilan University , Ziv Medical , Azrieli Faculty , Medical Center , Covid Vaccine , One Dose , Already Infected People , Covid 19 Vaccine Update , Covid Pandemic , மைக்கேல் எடெல்ஸ்டீன் , ஜிவ் மருத்துவ மையம் , இலன் பல்கலைக்கழகம் , ஆக்ஸ்ஃபர்ட் பல்கலைக்கழகம் , மதுக்கூடம் இலன் பல்கலைக்கழகம் , ஜிவ் மருத்துவ , மருத்துவ மையம் , ஒன்று டோஸ் , ஏற்கனவே நோய்த்தொற்றுக்கு உள்ளானவர் மக்கள் ,