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Model can predict how drug interactions influence antibiotic resistance


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Scientists have proposed a modelling framework which could predict how antibiotic resistance will evolve in response to different treatment combinations, according to a study published in eLife.
Microscopy image of
Enterococcus faecalis. Image credit: Janice Haney Carr, USCDCP (CC0)
The research could help doctors optimise the choice, timing, dose and sequence of antibiotics used to treat common infections, helping to halt the growing threat of antibiotic resistance to modern medicine.
“Drug combinations are a particularly promising approach for slowing resistance, but the evolutionary impacts of combination therapy remain difficult to predict, especially in a clinical setting,” explains first author Erida Gjini, Researcher at the Department of Mathematics, Instituto Superior Tecnico, University of Lisbon, Portugal. “Interactions between antibiotics c ....

United States , Kevin Wood , Erida Gjini , Janice Haney Carr , University Of Lisbon , National Institutes Of Health , Department Of Mathematics , National Science Foundation , University Of Michigan , Instituto Superior Tecnico , Associate Professor , Evolutionary Medicine , Special Issue , National Institutes , ஒன்றுபட்டது மாநிலங்களில் , கெவின் மரம் , ஜானிஸ் ஹேநீ கார் , பல்கலைக்கழகம் ஆஃப் லிஸ்பன் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , துறை ஆஃப் கணிதம் , தேசிய அறிவியல் அடித்தளம் , பல்கலைக்கழகம் ஆஃப் மிச்சிகன் , இந்‌ஸ்டிடூடோ உயர்ந்தது டெக்னிகோ , இணை ப்ரொஃபெஸர் , பரிணாம வளர்ச்சி மருந்து , சிறப்பு பிரச்சினை ,

PigProgress - Ventilation does not spread MRSA outside pig houses


PigProgress
Ventilation does not spread MRSA outside pig houses
Danish researchers put ventilation to the test in an attempt to see if methicillin-resistant Staphylococcus aureus (MRSA) could also spread outside pig houses.
The airborne spread of livestock-associated MRSA (LA-MRSA) through pig house ventilation hardly appears to be a source of infection for people outside the pig houses. That was the conclusion of recent Danish research, conducted by scientists from the Statens Serum Institut, the Technical University of Denmark as well as Aarhus University. The study was published in the peer-reviewed magazine
Frontiers in Veterinary Science.
MRSA bacteria when viewed through a microscope. - Photo: CDC/ Janice Haney Carr ....

Janice Haney Carr , Technical University Of Denmark , Aarhus University , Statens Serum Institut , Technical University , Janice Haney , ஜானிஸ் ஹேநீ கார் , தொழில்நுட்ப பல்கலைக்கழகம் ஆஃப் டென்மார்க் , ஆர்ஹஸ் பல்கலைக்கழகம் , தொழில்நுட்ப பல்கலைக்கழகம் , ஜானிஸ் ஹேநீ ,