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Israeli Researchers Declare Significant Progress in Search for Coronavirus Cure

Israeli Researchers Declare Significant Progress in Search for Coronavirus Cure
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Choose Your Bond | ScienceBlogs


By jhalper
on May 30, 2011.
Two completely unrelated papers have got us thinking about chemical bonds. When we refer to chemical bonds, we generally mean covalent bonds: Atoms become wedded, sharing electrons, and breaking them apart takes energy. By comparison, other types of bonds are weak attractions - mere flirtations, or mild sparks between hydrogen and oxygen in passing water molecules.
So why would a researcher in organic chemistry - a field based on carbon, the king of covalent bonds - be investigating the properties of non-covalent, hydrophobic bonds? The answer, of course, is that they can be used to create materials with unique properties. Let s back up a minute. Hydrophobic bonds occur between hydrophobic - or water-hating - molecules in the presence of water. Water, it seems, is equally averse to contact with hydrophobic molecules, and sticking closely to their own kind turns out to be the most amicable arrangement for both. And, whil ....

Zvulun Elazar , Boris Rybtchinski , Institute Biological Chemistry Department , Biological Chemistry Department , உயிரியல் வேதியியல் துறை ,

Protein simulation, experiments unveil clues on origins of Parkinson's disease


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HERSHEY, Pa. Parkinson s disease is the second most common neurodegenerative disease and affects more than 10 million people around the world. To better understand the origins of the disease, researchers from Penn State College of Medicine and The Hebrew University of Jerusalem have developed an integrative approach, combining experimental and computational methods, to understand how individual proteins may form harmful aggregates, or groupings, that are known to contribute to the development of the disease. They said their findings could guide the development of new therapeutics to delay or even halt the progression of neurodegenerative diseases.
Alpha-synuclein is a protein that helps regulate the release of neurotransmitters in the brain and is found in neurons. It exists as a single unit, but commonly joins together with other units to perform cellular functions. When too many units combine, it can lead to the formation of Lewy bodies, which are associated w ....

Israel General , Hebrew University , Khalil Joron , Joanna Zamel , Nir Kalisman , Paz Drori , Jiaxing Chen , Eitan Lerner , Nikolay Dokholyan , National Center , Penn State Cancer Institute , National Institutes Of Health , Penn State College Of Medicine , Translational Science Institute , Passan Foundation , Israel Science Foundation , Milner Fund , Hebrew University Of Jerusalem , Michaelj Fox Foundation , College Of Medicine , Chemistry Department , Penn State College , Biological Chemistry Department , Sofia Zaer , National Institutes , Advancing Translational Sciences ,