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Lithium treats intellectual defects in mouse model of Bardet-Biedl Syndrome

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IMAGE: Image of cilia in a mouse brain using Scanning Electron Microscopy, imaged and processed by Calvin S. Carter.
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Credit: Calvin S. Carter
Mice with symptoms that mimic Bardet-Biedl Syndrome (BBS) have difficulty with learning and generating new neurons in the hippocampus. However, according to a new study by Thomas Pak, Calvin Carter, and Val Sheffield of the University of Iowa, published April 22nd in the journal
PLOS Genetics, these mental defects can be successfully treated with lithium.
BBS is a rare genetic disorder that causes intellectual disability, vision loss and obesity, and sometimes kidney problems and extra fingers and toes. It is one of several ciliopathies, which are diseases that stem from defective cilia tiny, finger-like projections on the surface of cells that play important roles in moving fluids, sensing the environment and signaling between cells. Pak, Carter, Sheffield and colleagues wanted to learn ....

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Researchers discover new way to monitor & prevent nerve cell deterioration after TBI

Researchers discover new way to monitor & prevent nerve cell deterioration after TBI
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

United States , Kyoo Shin , Roberta Bonomo , Andrewa Pieper , Case Western Reserve School Of Medicine , Brockman Foundation , Allen Initiative In Brain Health , Va Geriatric Research , Harrington Discovery Institute , Neuropathology Core Of Northwestern University , Neurosurgery Of Mcgovern Medical School , Neurotherapeutics Center At University Hospitals , University Hospitals , Morley Mather Chair , Translational Therapeutics Core , Cleveland Alzheimer , Disease Research Center , Clinical Care , Min Kyoo Shin , Associate Chief , Ohio Healthcare System , Case Western Reserve School , Case Western Reserve , Cleveland Clinic , Allen Initiative , Brain Health ,

Iowa and Ohio team finds strategy to protect developing brain from prenatal stress in mice

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New research from the University of Iowa and University Hospitals Cleveland Medical Center demonstrates that offspring can be protected from the effects of prenatal stress by administering a neuroprotective compound during pregnancy.
Working in a mouse model, Rachel Schroeder, a student in the UI Interdisciplinary Graduate Program in Neuroscience, drew a connection between the work of her two mentors, Hanna Stevens, MD, PhD, UI associate professor of psychiatry and Ida P. Haller Chair of Child and Adolescent Psychiatry, and Andrew A. Pieper, MD, PhD, a former UI faculty member, now Morley-Mather Chair of Neuropsychiatry at Case Western Reserve University and Investigator and Director of the Neurotherapeutics Center at the Harrington Discovery Institute, University Hospitals Cleveland Medical Center. ....

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Rotten Egg Gas Could Guard Against Alzheimer's Disease

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Neuroscience research articles are provided.
What is neuroscience? Neuroscience is the scientific study of nervous systems. Neuroscience can involve research from many branches of science including those involving neurology, brain science, neurobiology, psychology, computer science, artificial intelligence, statistics, prosthetics, neuroimaging, engineering, medicine, physics, mathematics, pharmacology, electrophysiology, biology, robotics and technology.
– What is neurology?
– Definition of neurology: a science involved in the study of the nervous systems, especially of the diseases and disorders affecting them.
– Neurology research can include information involving brain research, neurological disorders, medicine, brain cancer, peripheral nervous systems, central nervous systems, nerve damage, brain tumors, seizures, neurosurgery, electrophysiology, BMI, brain injuries, paralysis and spinal cord treatments. ....

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