E-Mail
IMAGE: Protein structure with the newly identified switch between a cysteine and lysine residue showing its structure and electron density. This discovery has wide-reaching implications for understanding and treating diseases. view more
Credit: K Tittmann
Proteins perform a vast array of functions in the cell of every living organism with critical roles in almost every biological process. Not only do they run our metabolism, manage cellular signaling and are in charge of energy production, as antibodies they are also the frontline workers of our immune system fighting human pathogens like the coronavirus. In view of these important duties, it is not surprising that the activity of proteins is tightly controlled. There are numerous chemical switches that control the structure and, therefore, the function of proteins in response to changing environmental conditions and stress. The biochemical structures and modes of operation of these switches were thought to be
E-Mail
IMAGE: A team led by Iain Drummond, Ph.D., director of the Kathryn W. Davis Center for Regenerative Biology and Aging at the MDI Biological Laboratory in Bar Harbor, Maine, has. view more
Credit: MDI Biological Laboratory
BAR HARBOR, MAINE Our kidneys are charged with the extraordinary task of filtering about 53 gallons of fluid a day, a process that depends on podocytes, tiny, highly specialized cells in the cluster of blood vessels in the kidney where waste is filtered that are highly vulnerable to damage.
In research at the MDI Biological Laboratory in Bar Harbor, Maine, a team led by Iain Drummond, Ph.D., director of the Kathryn W. Davis Center for Regenerative Biology and Aging, has identified the signaling mechanisms underlying podocyte formation, or morphogenesis. The discovery opens the door to the development of therapies to stimulate the regeneration of these cells, which are vital to ridding the body of toxins.
Credit: Flinders University
For the first time, international experts in psychology have built a framework to diagnose Compulsive Buying-Shopping Disorder - promising help for people struggling to manage their spending behaviour and mental wellbeing.
The new guidelines, published in the
Journal of Behavioral Addictions, confirms that excessive buying and shopping can be so serious as to constitute a disorder, giving researchers and clinicians new powers to develop more targeted interventions for this debilitating condition.
The international collaboration, led by Professor Mike Kyrios from Flinders University s Órama Institute for Mental Health and Wellbeing and Professor Astrid Müller from the Hannover Medical School in Germany, say evidence-based criteria for Compulsive Buying-Shopping Disorder (CBSD) are long overdue.
CurePSP awards three new Venture Grants for the study of PSP and CBD
Studies will focus on toxic protein in the brain and genetic factors
News provided by
Share this article
Share this article
NEW YORK, April 15, 2021 /PRNewswire/ CurePSP has awarded Venture Grants to three researchers studying tau protein pathology and genetic factors in progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD). Each grant is for $100,000.
Dr. Rohan de Silva of UCL Queen Square Institute of Neurology in London has received a grant for his study of the propagation of toxic tau protein in the brain. The aim of this project is to understand how healthy tau is converted to toxic strains related to PSP and CBD and to identify their imprinted defects that enable the strain-specific progression. As Dr. de Silva explains, Tau protein is essential for healthy nerve cells, but tau gone bad drives the devastating damage and progression of PSP, CBD, and other diseases involving the tau
For 18 hours a day, Andreas Greinacher and his team at Germany s Greifswald University Hospital have pored over blood samples from across Germany and Austria. Their mission: Trying to figure out how and why potentially deadly blood clots have appeared in a handful of patients who received AstraZeneca s coronavirus vaccine.
Matthias Schrader/AP
Potentially deadly blood clots have appeared in a handful of patients who received AstraZeneca s coronavirus vaccine, despite no link being established with the vaccine. No link has been established with the vaccine, widely used in Europe and other countries, including Canada and India, and under review for possible approval in the United States.