Genentech Launches $1B+ RNA Collaboration with Ribometrix
Ribometrix has shown that several RNAs associated with disease contain structural pockets clefts and crevices (highlighted) that are amenable to targeting with small molecules. Genentech, a member of the Roche Group, will apply Ribometrix’s discovery platform to discover, develop and commercialize small molecule drug candidates against RNA targets, through a collaboration that could generate more than $1 billion for the Durham, NC-based company. [Ribometrix]
January 6, 2021
Ribometrix has shown that several RNAs associated with disease contain structural pockets clefts and crevices (highlighted) that are amenable to targeting with small molecules. Genentech, a member of the Roche Group, will apply Ribometrix’s discovery platform to discover, develop and commercialize small molecule drug candidates against RNA targets, through a collaboration that could generate more than $1 billion for the Durham, NC-based company. [Ri
December 21, 2020
December 21, 2020 | Funding updates around the life sciences including cash for a handheld mass spec device, Series D for oncolytic immunotherapy, a new company launch in allogenic CAR-NK cells, AI-powered cell classification, a 3-D sequencing platform, and more.
$170M: Israeli ‘Digital Health First’ VC Firm
OTV (formerly Olive Tree Ventures), Israel’s ‘digital health first’ venture capital firm, today announced the closing of a fund with a total value of $170M. OTV also announced their new name and the appointment of a new Head of Asia Pacific to spearhead the fund’s expansion into the region’s market. OTV is the only venture capital fund in Israel whose primary focus is digital health, specializing in supporting their portfolio companies reach maturity, refine execution, tackle regulatory hurdles and ensure a global imprint on validated products. Over the course of the past five years, OTV has prioritized investment in digital health
A new startup is working towards using a patient’s own genetic makeup to fight cancer.
Catamaran Bio, a startup at LabCentral in Cambridge, was established to consider the potency of natural killer (NK) cells in fighting cancer, and so far, it has raised $42 million from five venture capital companies including the founding investor, SV Health Investors, of Boston.
“This was a group of people who had wanted to do something together for a long time,” said Houman Ashrafian, managing partner of SV Health Investors.
Immunotherapy drugs such as Kymriah, Novartis’s leukemia therapy, have shown promising results for the treatment of blood cancers. The approach, also called CAR-T therapy, relies on harvesting patients’ T cells and genetically altering them to target the cancer after they are reintegrated into the patient’s genetic makeup. Earlier in 2020, researchers at MD Anderson Cancer Centre announced they achieved a “73% response rate with a CD19-targeting therapy d
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