Apr 26, 2021
Here s today s feel-good story:
Obesity is known to be an inflammatory disease, a defensive reaction of the body to stress by excess nutrients.
With this knowledge, a group of researchers at the Spanish National Cancer Research Centre decided to try to find a way to fight obesity by preventing inflammation.
They found out that the drug Digoxin, used for heart disease, reduces inflammation and leads to 40% weight loss in mice that are obese with no side effects.
“Since no effective treatments for obesity and metabolic syndrome are available, digoxin may represent an effective therapeutic option,” the researchers wrote.
Good News Network
Apr 25, 2021
It has long been known that obesity is an inflammatory disease, i.e. a chronic defensive reaction of the body to stress caused by excess nutrients.
Based on this knowledge, a group of researchers led by Nabil Djouder, Head of the Growth Factors, Nutrients and Cancer Group at the Spanish National Cancer Research Centre (CNIO), decided to try to fight obesity by preventing inflammation and they succeeded.
Their paper, published this month in Nature Metabolism, shows that digoxin, a drug already in use against heart diseases, reduces inflammation and leads to a 40% weight loss in obese mice, without any side effects.
USP7 inhibitors could increase the anticancer effects of CDK1 compounds in cancer patients
Understanding the components that control cell division is fundamental to understanding how life works and how alterations in this delicate process can cause diseases such as cancer.
It was precisely the discoveries of key regulators of the cell cycle and their implications for processes such as cancer, that won the British scientists R. Timothy Hunt and Paul M. Nurse and the American scientist Leland H. Hartwell the 2001 Nobel Prize in Physiology or Medicine.
A study led by Óscar Fernández-Capetillo, Head of the Genomic Instability Group at the Spanish National Cancer Research Centre (CNIO) and published this week in The
Go
Nature Metabolism. CNIO researchers discover that a drug already in use in humans corrects obesity in mice, with no side effects
Functional food
Obese mice were treated with digoxin, a drug used to treat several heart conditions
The approach of the study, published in Nature Metabolism, was to treat obesity as an inflammatory disease It has long been known that obesity is an inflammatory disease, i.e. a chronic defensive reaction of the body to stress caused by excess nutrients. Based on this knowledge, a group of researchers led by
Nabil Djouder, Head of the Growth Factors, Nutrients and Cancer Group at the Spanish National Cancer Research Centre (CNIO), decided to try to fight obesity by preventing inflammation – and they succeeded. Their paper, published this week in
Credit: CNIO
Understanding the components that control cell division is fundamental to understanding how life works and how alterations in this delicate process can cause diseases such as cancer. It was precisely the discoveries of key regulators of the cell cycle and their implications for processes such as cancer, that won the British scientists R. Timothy Hunt and Paul M. Nurse and the American scientist Leland H. Hartwell the 2001 Nobel Prize in Physiology or Medicine. A study led by Óscar Fernández-Capetillo, Head of the Genomic Instability Group at the Spanish National Cancer Research Centre (CNIO) and published this week in