Latest Breaking News On - ஸூஸ ஜூனியர் - Page 3 : comparemela.com

Abstract To characterize the genetic basis of facial features in Latin Americans, we performed a genome-wide association study (GWAS) of more than 6000 individuals using 59 landmark-based measurements from two-dimensional profile photographs and ~9,000,000 genotyped or imputed single-nucleotide polymorphisms. We detected significant association of 32 traits with at least 1 (and up to 6) of 32 different genomic regions, more than doubling the number of robustly associated face morphology loci reported until now (from 11 to 23). These GWAS hits are strongly enriched in regulatory sequences active specifically during craniofacial development. The associated region in 1p12 includes a tract of archaic adaptive introgression, with a Denisovan haplotype common in Native Americans affecting particularly lip thickness. Among the nine previously unidentified face morphology loci we identified is the VPS13B gene region, and we show that variants in this region also affect midfacial morphology

United statesContreras sieckM granados riverosUniversidad nacionalJ felisberto menezes cavalheiroMarseille universitSouza jrEcole doctoraleM ballesteros romeroD rogel diazI jafet morenoExcellence initiative of aixNational natural science foundation of chinaUniversity of burgundyTechnology committee of shanghai municipalitySantander research