Study shows how proteins work in concert to resolve DNA double-strand breaks
From cancer treatment to sunlight, radiation and toxins can severely damage DNA in both harmful and healthy cells. While the body has evolved to efficiently treat and restore damaged cells, the mechanisms that allow this natural repair remain misunderstood.
In a new study, Northwestern University researchers have used cryogenic electron microscopy (cryo-EM) to visualize this process by illuminating the mysterious cycle of DNA breakage sensing and repair. The researchers believe this new information could potentially form the basis for understanding how cells respond to chemotherapy and radiation and potentially even lead to improved cancer treatments.
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Understanding how DNA repairs itself may lead to better cancer treatments
From cancer treatment to sunlight, radiation and toxins can severely damage DNA in both harmful and healthy cells. While the body has evolved to efficiently treat and restore damaged cells, the mechanisms that allow this natural repair remain misunderstood.
In a new study, Northwestern University researchers have used cryogenic electron microscopy (cryo-EM) to visualize this process by illuminating the mysterious cycle of DNA breakage sensing and repair. The researchers believe this new information could potentially form the basis for understanding how cells respond to chemotherapy and radiation and potentially even lead to improved cancer treatments.
Northwestern Now
Northwestern Junior Abigail Roston wins highly competitive congressional scholarship
Truman Scholar Abigail Roston
EVANSTON, Ill. - Northwestern University junior Abigail Roston has received the highly competitive Harry S. Truman Scholarship, a $30,000 award that supports graduate education for outstanding students dedicated to public service and in Roston’s case, criminal justice reform.
A junior studying American history, legal studies and data science in the Weinberg College of Arts and Sciences, she plans to attend law school, join the ranks of federal public defenders, specializing in juvenile justice, and ultimately win appointment to the office of U.S. solicitor general, where Roston believes she would be ideally situated to reform the system from the inside out.
Understanding how DNA repairs itself may lead to better cancer treatment eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.
Four professors named Guggenheim fellows northwestern.edu - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from northwestern.edu Daily Mail and Mail on Sunday newspapers.