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IMAGE: Anna Rommel, PhD, Instructor, Department of Psychiatry, Icahn School of Medicine at Mount Sinai view more
Credit: Mount Sinai Health System
New York, NY - Major depressive disorder is highly prevalent, with one in five people experiencing an episode at some point in their life, and is almost twice as common in women than in men. Antidepressants are usually given as a first-line treatment, including during pregnancy, either to prevent the recurrence of depression, or as acute treatment in newly depressed patients. Antidepressant use during pregnancy is widespread and since antidepressants cross the placenta and the blood-brain barrier, concern exists about potential long-term effects of intrauterine antidepressant exposure in the unborn child.
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IMAGE: A photo collage of all nine of the 2021 Vilcek Foundation Prizewinners - Including Science Prizewinners Ruth Lehmann, Mohamed Abou Donia, Ibrahim Cissé, and Silvi Rouskin. Other prizewinners pictured are. view more
Credit: Courtesy of the Vilcek Foundation
NEW YORK, April 6, 2021 The Vilcek Foundation has launched an online celebration to honor the recipients of the 2021 Vilcek Foundation Prizes. Formatted as a microsite, the online celebration recognizes and shares the accomplishments of the 2021 Vilcek Foundation Prizewinners in lieu of the Vilcek Foundation s annual gala.
Awarded annually, the Vilcek Foundation Prizes celebrate the value and importance of immigration by recognizing the outstanding achievements of foreign-born individuals in the United States. In 2021, the Vilcek Foundation Prizes are awarded in Biomedical Science, in Filmmaking, and for Excellence in Public Service.
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IMAGE: A drawing series by artist Virginia Lopez-Anido that was inspired by research by her sister, Camila Lopez-Anido, a postdoctoral scholar at Stanford who studies cellular development in plants. view more
Credit: Virginia Lopez-Anido
How do we become a complex, integrated multicellular organism from a single cell?
While developmental biologists have long researched this fundamental question, Stanford University biologist and HHMI investigator Dominique Bergmann s recent work on the plant Arabidopsis thaliana has uncovered surprising answers.
In a new study, published April 5 in
Developmental Cell, led by Bergmann and postdoctoral scholar Camila Lopez-Anido, researchers used single-cell RNA sequencing technologies to track genetic activity in nearly 20,000 cells as they formed the surface and inner parts of an Arabidopsis leaf. Through this highly detailed technique, the researchers captured transient and rare cell states and found a surprising abundance
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We ve all heard the adage, If at first you don t succeed, try, try again, but new research from Carnegie Mellon University and the University of Pittsburgh finds that it isn t all about repetition. Rather, internal states like engagement can also have an impact on learning.
The collaborative research, published in
Nature Neuroscience, examined how changes in internal states, such as arousal, attention, motivation, and engagement can affect the learning process using brain-computer interface (BCI) technology. Findings suggest that changes in internal states can systematically influence how behavior improves with learning, thus paving the way for more effective methods to teach people skills quickly, and to a higher level of proficiency.
Credit: Monash University
AUSTRALIAN - LED INTERNATIONAL RESEARCH TEAM GENERATES THE FIRST MODEL OF EARLY HUMAN EMBRYOS FROM SKIN CELLS
In a discovery that will revolutionize research into the causes of early miscarriage, infertility and the study of early human development - an international team of scientists led by Monash University in Melbourne, Australia has generated a model of a human embryo from skin cells.
The team, led by Professor Jose Polo, has successfully reprogrammed these fibroblasts or skin cells into a 3-dimensional cellular structure that is morphologically and molecularly similar to human blastocysts. Called iBlastoids, these can be used to model the biology of early human embryos in the laboratory.