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Research project aims to make CAR-T-cell therapy safer and more effective

Researchers identify new immunotherapy treatment target for acute myeloid leukemia in children

Researchers identify new immunotherapy treatment target for acute myeloid leukemia in children Researchers have identified a gene expressed in children with acute myeloid leukemia (AML) that could serve as a new immunotherapy treatment target, according to a new study published today in Blood Advances, a journal of the American Society of Hematology. The study, co-authored by researchers with Nemours Children s Health System, outlines the process and potential path for new immunotherapy drugs that improve survival and reduce treatment-related toxicity in children with AML. Leukemia is the most common cancer in children and teens, and AML accounts for nearly one-fourth of those cases. AML is a fast-growing cancer that typically starts in immature bone marrow cells.

Study finds potential therapeutic target for pediatric acute myeloid leukemia

 E-Mail ORLANDO, Fla. (May 3, 2021) - Researchers have identified a gene expressed in children with acute myeloid leukemia (AML) that could serve as a new immunotherapy treatment target, according to a new study published today in Blood Advances, a journal of the American Society of Hematology. The study, co-authored by researchers with Nemours Children s Health System, outlines the process and potential path for new immunotherapy drugs that improve survival and reduce treatment-related toxicity in children with AML. Leukemia is the most common cancer in children and teens, and AML accounts for nearly one-fourth of those cases. AML is a fast-growing cancer that typically starts in immature bone marrow cells.

Avocado discovery may point to leukemia treatment

Avocado discovery may point to leukemia treatment A compound in avocados may ultimately offer a route to better leukemia treatment, says a new University of Guelph study. The compound targets an enzyme that scientists have identified for the first time as being critical to cancer cell growth, said Dr. Paul Spagnuolo, Department of Food Science. Published recently in the journal Blood, the study focused on acute myeloid leukemia (AML), which is the most devastating form of leukemia. Most cases occur in people over age 65, and fewer than 10 per cent of patients survive five years after diagnosis. Leukemia cells have higher amounts of an enzyme called VLCAD involved in their metabolism, said Spagnuolo.

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