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RESEARCH TRIANGLE PARK, N.C., May 25, 2021 /PRNewswire/ Asklepios BioPharmaceutical, Inc. (AskBio), a wholly owned and independently operated subsidiary of Bayer AG, announced that the U.S. Food & Drug Administration (FDA) has cleared its Investigational New Drug (IND) application for LION-101 to proceed in a Phase 1/2 clinical study. LION-101 is a novel recombinant adeno-associated virus (rAAV) based vector being developed as a one-time intravenous infusion for the treatment of patients with Limb-Girdle Muscular Dystrophy Type 2I/R9 (LGMD2I/R9).
LION-101 will be evaluated in a Phase 1/2 multicenter study to evaluate a single intravenous (IV) infusion in adult and adolescent subjects with genotypically confirmed LGMD2I/R9. AskBio plans to initiate dosing for the LION-101 Phase 1/2 clinical study in the first half of 2022.
There are several different types of breast cancer. They can occur in different parts of the breast.
Apart from skin cancers, breast cancer is the most common cancer in females in the United States. This is according to the American Cancer Society (ACS).
The ACS also states that a female in the U.S. has a 13% chance of developing breast cancer. However, breast cancer can affect people of any sex or gender.
To understand more about the types of breast cancer, a person may find it helpful to learn about the anatomy of the breast.
This article will look into the different types of breast cancer, including their symptoms, outlooks, and treatment options. It will also discuss breast cancer screening and when to contact a doctor.
Living with uncomfortably large breasts is about a lot more than finding the right bra (Karolina Grabowska/Pexels)
Large breasts are celebrated in a patriarchal society that objectifies women’s bodies. But, for these four women, having uncomfortably large breasts has caused painful and embarrassing situations throughout their lives.
“In high school, a male teacher joined in with a group of schoolgirls who were making fun of how big my boobs were. It was humiliating,” recalls Thelmay Wahl. Now, 67, Wahl has experienced a lifetime of physical and emotional pain.
Being mocked, whispered about, and stared at is an almost daily occurrence for women who have very big breasts.
Rare disorders of sexual development that affect intersex people
The patient in China was told she had what is known as a 46 XY disorder of sexual development , part of a family of rare conditions affecting people who are sometimes described as intersex.
A 46 XY disorder means someone has the male Y chromosome but may have ambiguous, underdeveloped or missing genital organs and might be raised as either a boy or a girl.
One type of this known as Swyer syndrome is thought to occur in about one in 80,000 births, according to one estimate.
Medical experts say it can sometimes be hard to tell whether a child s organs are more like a boy s or a girl s, for example if they have testes which are not fully developed.
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