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The Lancet Publishes Results from Pivotal Global Phase 3 Program Evaluating RINVOQ® in Atopic Dermatitis

ABBVie today announced The Lancet published primary analysis results from the pivotal global Phase 3 clinical trials Measure Up 1, Measure Up 2 and AD Up evaluating RINVOQ ® in adults and adolescents with moderate to severe atopic dermatitis who were candidates for systemic treatment. The results were published in two separate manuscripts as part of the May 22, 2021 issue of The Lancet. The publication of .

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The Lancet Publishes Results from Pivotal Global Phase 3 Program Evaluating RINVOQ® (upadacitinib) in Atopic Dermatitis

The Lancet Publishes Results from Pivotal Global Phase 3 Program Evaluating RINVOQ® (upadacitinib) in Atopic Dermatitis News provided by Share this article NORTH CHICAGO, Ill., May 24, 2021 /PRNewswire/ AbbVie (NYSE: ABBV) today announced The Lancet published primary analysis results from the pivotal global Phase 3 clinical trials – Measure Up 1, Measure Up 2 and AD Up – evaluating RINVOQ ® (upadacitinib) in adults and adolescents with moderate to severe atopic dermatitis who were candidates for systemic treatment. The results were published in two separate manuscripts as part of the May 22, 2021 issue of The Lancet. The publication of Measure Up 1 and Measure Up 2 shares efficacy and safety results of patients treated with upadacitinib (15 mg or 30 mg, once daily) monotherapy versus placebo for 16 weeks.

United statesEuropean commissionExchange commissionAbbvie incImportant safetyMississippi riverFull prescribing informationAllergan aestheticsPrivate securities litigation reform actQuarterly reportsGlobal epidemiologyAnn nutr metabRev dis primersAtopic dermatitisHealthcare claims dataEvaluate efficacy

Voxelotor in adolescents and adults with sickle cell disease (HOPE): long-term follow-up results of an international, randomised, double-blind, placebo-controlled, phase 3 trial

Voxelotor in adolescents and adults with sickle cell disease (HOPE): long-term follow-up results of an international, randomised, double-blind, placebo-controlled, phase 3 trial
thelancet.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from thelancet.com Daily Mail and Mail on Sunday newspapers.

United statesClin hemorheol microcircAmerican society of hematologyHematology am soc hematol educ programNational institutes of healthNational heart lungBlood instituteRev dis primersHeart lungDatabase sys revClin investEnglj medHemorheol microcircஒன்றுபட்டது மாநிலங்களில்அமெரிக்கன் சமூகம் ஆஃப் ஹீமாட்டாலஜிதேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம்

Effective interventions to address maternal and child malnutrition: an update of the evidence

Effective interventions to address maternal and child malnutrition: an update of the evidence
thelancet.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from thelancet.com Daily Mail and Mail on Sunday newspapers.

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Novartis investigational oral therapy iptacopan (LNP023) receives FDA Breakthrough Therapy Designation for PNH and Rare Pediatric Disease Designation for C3G

Posted December 16th, 2020 for Novartis Paroxysmal nocturnal hemoglobinuria (PNH) is a rare and life-threatening blood disorder, resulting in debilitating symptoms that can impact patients’ quality of life 1–3 C3 glomerulopathy (C3G) is a rare renal disease, affecting young patients with a poor prognosis and significant unmet need 4-5 With potential to be the first oral treatment for a range of complement-driven diseases, complement factor B inhibitor iptacopan targets the underlying cause of these conditions through its action on the complement system’s alternative pathway 6,7 Iptacopan is in development for PNH, as well as C3G and several other rare renal diseases including IgA nephropathy (IgAN), atypical hemolytic uremic syndrome (aHUS), and membranous nephropathy (MN); first FDA filings anticipated in 2023

United statesEric althoffIsabella zinckSamir shahThomas hungerbuehlerPhil mcnamaraSloan simpsonNephrol hypertensDrug administrationNovartis oncology communicationsInternational paroxysmal nocturnal hemoglobinuria registryNovartis us external communicationsExchange commissionEuropean society for bloodMeeting of the american society nephrologyMetabolic communications