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Studies focus on breast cancer risk
They provide new info on which genes women should be worried about By MARILYNN MARCHIONE, Associated Press
Published: January 26, 2021, 6:02am
Share: A woman gets a mammogram at the University of Michigan Cancer Center in Ann Arbor, Mich. (Kimberly P. Mitchell/Detroit Free Press)
Two large studies give a much sharper picture of which inherited mutations raise the risk of breast cancer for women without a family history of the disease, and how common these flawed genes are in the general population.
Doctors say the results published Wednesday by the New England Journal of Medicine can help women make better decisions about screening, preventive surgery or other steps.
Jan 21, 2021
(AP) Two large studies give a much sharper picture of which inherited mutations raise the risk of breast cancer for women without a family history of the disease, and how common these flawed genes are in the general population.
Doctors say the results published Wednesday by the New England Journal of Medicine can help women make better decisions about screening, preventive surgery or other steps.
Although this sort of genetic testing isn’t currently recommended for the general population, its use is growing and many people get it from tests sold directly to consumers.
The new work shows that the risk conferred by some genes “is very high,” Mary-Claire King wrote in an email. King, a University of Washington scientist, had no role in the new studies but discovered the first breast cancer predisposition gene, BRCA1.
Marilynn Marchione
FILE - In this May 22, 2015 photo, a woman gets a mammogram at the University of Michigan Cancer Center in Ann Arbor, Mich. Two large studies, published Wednesday, Jan. 20, 2021, by the New England Journal of Medicine, give a much sharper picture of which inherited mutations raise the risk of breast cancer for women without a family history of the disease, and how common these flawed genes are in the general population. Doctors say the results can help women make better decisions about screening, preventive surgery or other steps. (Kimberly P. Mitchell/Detroit Free Press via AP, File) January 20, 2021 - 2:03 PM