June 14, 2021 PET imaging with a gallium-68 (Ga-68)-labeled fibroblast activation protein inhibitor (FAPI) shows promise as an effective way to identify and monitor pulmonary fibrosis, according to animal study findings presented at the virtual 2021 Society of Nuclear Medicine and Molecular Imaging (SNMMI) annual meeting.
The technique could add molecular imaging to the lung disease toolbox and perhaps reduce the number of biopsies, said study lead author Carolina de Aguiar Ferreira, PhD, of the University of Wisconsin-Madison in a statement released June 12 by the SNMMI. Further validation of [PET/CT with gallium-68] for the detection and monitoring of pulmonary fibrosis would make this molecular imaging tool the first technique for early, direct, and noninvasive detection of disease, she said. It would also provide an opportunity for molecular imaging to reduce the frequency of lung biopsies, which carry their own inherent risks.
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