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Vaccines dramatically reduces COVID-19 risk, experts say, though infections still possible Updated Apr 03, 2021; Posted Apr 03, 2021 Pfizer-BioNTech COVID-19 doses are prepared at a vaccine outreach clinic at Mt. Zion Baptist Church in Kalamazoo, Michigan on Tuesday, March 23, 2021. The clinic was put on by the Kalamazoo County Health Department with volunteers from Mt. Zion. (Joel Bissell | MLive.com) Facebook Share Yes, the COVID-19 vaccine works. After two weeks, one vaccine shot is 80% effective at preventing infections, while a second shot carries 90% effectiveness, according to a new CDC study. “Our data from the CDC today suggest that vaccinated people do not carry the virus,” said CDC Director Dr. Rochelle Walensky in an MSNBC interview from Tuesday, March 30.

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