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Do purines influence cancer development?

Credit: Laura Alvarez, CeMM Numerous disease development processes are linked to epigenetic modulation. One protein involved in the process of modulation and identified as an important cancer marker is BRD4. A recent study by the research group of Giulio Superti-Furga, Principal Investigator and Scientific Director at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, now shows that the supply of purines as well as the purine synthesis of a cell can influence BRD4 activity and thus play a role in the carcinogenesis process. The findings were published in Nature Metabolism. Chromatin is a central component of the cell nucleus. It refers to the complex of the approximately two-meter-long human DNA with proteins that organize it so that - depending on the cell type - certain genes are activated or deactivated. In order to be able to adapt to diverse situations and influences, cells read the information relevant to them from the DNA. If this process

Why Does Eating Too Much Salt Make Us More Susceptible to Covid?

Well we already know all too well, according to research, that eating a diet too high in sodium can lead to heart and blood pressure problems. But now a new study has revealed it can also have a negative effect on our immune systems. That means we may be more susceptible to getting sick due to illnesses caused by bacteria and viruses. And yes, that includes Covid-19. But how exactly? Get our free mobile app The study leading to these insights was was done in 2015. But recently it was published in a medical journal called Circulation. Sadly, the higher the amount of sodium we have in our blood has an effect on how our white blood cells are able to prepare to defend our bodies when unhealthy cells are discovered.

One Major Side Effect of Eating Too Much Salt, New Study Says

One Major Side Effect of Eating Too Much Salt, New Study Says © Provided by Eat This, Not That! salting popcorn A lot of you were recently surprised to learn about the toxic fat that s more harmful than cholesterol. In other news on unexpected nutrition dangers, a study has just discovered that the amount of salt you eat could make you more vulnerable to illness from bacteria (like this deadly food poisoning from pasta) and viruses (like COVID-19). A newly published study in the journal Circulation sought to deepen understanding that scientists gained from a study in 2015. In that previous study, the research team discovered that elevated amounts of sodium in the blood affected how a certain type of white blood cell prepares to react when it senses an unhealthy cell. But even at the conclusion of that study, says Dr. Sabrina Geisberger of the Berlin Institute for Medical Systems Biology (BIMSB), the scientists still didn t know what was happening in the cells.

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