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National efforts to develop a coronavirus disease 2019 (COVID-19) vaccine at “warp speed” will likely yield a safe and effective vaccine by early 2021. However, this important milestone is only the first step in an equally important challenge: getting a majority of the US public vaccinated. In a September 2020 survey of 10 093 US adults, only 51% indicated that they were definitely or probably willing to be vaccinated with a novel COVID-19 vaccine, 25% reported that they were probably not willing to get the vaccine, and 24% reported that it is unlikely that they would be vaccinated. 1 This survey further revealed that acceptance was lower among Black individuals (32%, 263 of 822); those with lower educational attainment (47%, 676 of 1438 among those with high school or less education) compared with college graduates (56%, 1673 of 2988) or those with a postgraduate education (63%, 1693 of 2668); and among Republican voters (44%, 1817 of 4129).

University of pennsylvaniaUnited statesFagin hallBarack obamaGeorgew bushAlisonm buttenheimCenters for diseaseQantas airlinesNational institutes of healthNational institute onDrug administrationAdvisory committee on immunization practicesProducts advisory committeeUniversity of pennsylvania school nursingOperation warp speedVaccine free