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Bruker s Molecular Phenomics Research Tools Enable New Insights into Long COVID and Post-Acute Metabolic Abnormalities

Bruker’s Molecular Phenomics Research Tools Enable New Insights into ‘Long COVID’ and Post-Acute Metabolic Abnormalities on May 21 2021 12:12 AM Australian National Phenome Centre Integrates Quantitative NMR and MS Assay Platform for Risk Assessment and Longitudinal Monitoring of Post-Acute COVID-19 Syndrome (PACS) PERTH, Australia (BUSINESS WIRE) A clinical research collaboration on COVID-19 pheno-conversion and subsequent pheno-reversion has discovered transient and persistent systemic changes of the molecular signatures in patient blood samples three months after the acute COVID-19 disease phase. These biochemical abnormalities, identified by a quantitative, label-free assay platform integrating nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS), relate to ongoing ‘long COVID’ symptoms, which persist post-acute infection and can affect more than half of the recovered COVID patients - even six months after infection.

The role of small molecule NMR in medicinal chemistry

The role of small molecule NMR in medicinal chemistry Supported by: ABOUT THIS WEBINAR Since its early days, nuclear magnetic resonance (NMR) has played an important role in the pharmaceutical industry. NMR is traditionally used by medicinal chemists for structure elucidation of both synthesised molecules and active compounds isolated from natural sources. However, it can also be a valuable tool for reaction monitoring, the characterisation of solution conformations, the investigation of metabolites, hit-to-lead optimisation and quantitation. In this webinar, Kathleen Farley (Senior Principal Scientist, R&D, Pfizer Inc) will describe how NMR spectroscopy is integrated into the Pfizer drug discovery pipeline and how the technique is used in a walk-up environment by medicinal chemists and NMR scientists to solve challenging drug discovery problems.

New leaders for Swiss tech startups Startupticker ch | The Swiss Startup News channel

The Zurich-based startup offering a forecasting tool for the foodservice industry has made changes in its leadership. Former CTO Roman Lickel is now the company’s Managing Director. Roman takes over the role from Simon Michel, with whom he built Prognolite. “The last few years have been an incredibly intense and beautiful time. Although I believe in success more than ever, I see that Prognolite can be better led by my co-founder Roman together with Nico with the somewhat changed focus. As a shareholder, however, I will remain closely connected to Prognolite,” says Simon.  For its platform that allows over 40,000 tenants to rent everyday objects, Sharely has welcomed Lucie Rein as its new CEO to further grow Sharely as a leading sharing platform. Lucie brings several years of experience having worked at companies such as the startups Farmy and Too Good To Go and leading global companies Barilla and Nestlé, Danone and Ikea. Sharely has seen remarkable growth since its foundat

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