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 E-Mail Daily infusions of albumin provide no significant health benefit to patients hospitalised with advanced liver disease, over and above standard care , finds a large-scale multicentre trial led by UCL researchers. Albumin is a protein made in the liver that prevents fluid leaking from the bloodstream to other body tissues and carries various substances throughout the body, such as hormones or enzymes. In people with liver disease, low albumin levels are associated with an increased risk of death among hospitalised patients who have cirrhosis, and laboratory studies have shown albumin to have an anti-inflammatory effect. Therefore, albumin infusions are considered the best fluid for patients with cirrhosis and are an integral part of clinical care.

United kingdomCity ofGlasgow cityDigestive healthInstitute for liverUniversity of nottinghamLondon school of medicineUniversity of glasgowThurrock university hospitalsDivision of medicineQueen mary university of londonDepartment of healthHealth innovation challenge fundPrincipal investigatorProfessor alastairo brienNew england journal