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Gene Mutations Linked to Worse Outcomes from Leukemia in Hispanic and Latino Children
Penn State, February 2, 2021
A combination of genetic mutations may explain the higher incidence of and poorer outcomes from pediatric leukemia in Hispanic and Latino children, according to Penn State College of Medicine researchers. They said a novel therapeutic drug combination as well as testing for these mutations may help address the disparity.
Hispanic and Latino children are between 1.2 and 1.75 times more likely to develop B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, than non-Hispanic and Latino children. They also have a 40% higher death rate than their counterparts after correcting for socioeconomic factors. Dr. Sinisa Dovat, a researcher and pediatric oncologist at Penn State Children’s Hospital and Penn State Cancer Institute, partnered with Dr. Gordana Raca of Children’s Hospital Los Angeles and Kimberly J. Payne of Loma Linda University to u
During their waking hours, dancers were tasked with different challenges like playing games and posting selfies on social media. Some entertainment events still took place at the center some pre-recorded and some live but no spectators were allowed.
The dance marathon was first organized in 1973 by a group of students seeking an opportunity to give back to their community. It has since grown into the largest student-run philanthropy in the world, both in revenue and volunteer participation. Each year, more than 16,500 student volunteers participate in the year-long fundraising efforts to benefit the event s sole beneficiary, Four Diamonds at Penn State Children s Hospital.
Pennsylvania State University’s 46-hour dance marathon, known as THON, raised $10.6 million for pediatric cancer research and patient support this weekend, despite having to adjust to a virtual format because of the pandemic. That’s only about a million shy of last year’s total, when more than 700 dancers and thousands of spectators were able to pack the Bryce Jordan Center. And it comes in a .
Jillian Pikora The Penn State THON dance marathon concluded Sunday in Pennsylvania.Typically thousands of dancers and volunteers gather at Penn State s Bryce Jordan Center, where they stay on their feet for 46 hours straight to raise money for pediatric cancer research.Those dancers participated from their own homes this year. Last year, students were able to raise more than $11.5 million for the Four Diamonds Fund at Penn State Children’s Hospital.This year s total was $10,638,078.62This is a less than last year s total, but given the changes due to the pandemic it is still very impressive. The current record is $13.34 million raised in 2014. Over the past 47 years, the 46 hour dance marathon has raised over $178 million. The money raised helps children and their families fight cancer.THON is a student-run philanthropy committed to enhancing the lives of children and families impacted by childhood cancer. Its mission is to provide emotional and financial support