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Scientists decipher the structure of protein found in parasites that cause neglected tropical diseases
Brazilian researchers have managed to decipher the structure of a protein found in parasites that cause neglected tropical diseases, paving the way to the development of novel medications. Thanks to the discovery it will be possible to seek more potent molecules capable of destroying the pathogens directly, with fewer adverse side-effects for patients.
The study detailed the structural characteristics of the protein deoxyhypusine synthase (DHS), found in
Brugia malayi, one of the mosquito-borne parasites that cause elephantiasis, and in
Leishmania major, the protozoan that causes cutaneous leishmaniasis.