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Charcot Marie Tooth and Dejerine-Sottas syndrome are groups of diseases that involve the breakdown of the myelin sheath covering nerve axons.
As this myelin sheath breaks down, people who have these disorders suffer nerve damage in the arms and legs those with Dejerine-Sottas disease may never walk or may lose the ability to walk by the time they are teenagers.
Researchers have known that a protein called PMP22, which is important for nerve myelin, is likely involved in the disease. But because the protein is so small and part of the cell membrane, it s difficult to study. Now, an interdisciplinary team from the University of Michigan and Vanderbilt University have used a cutting-edge technique called ion mobility-mass spectrometry (IM-MS) to show that an unstable, mutant version of the PMP22 protein associates with another mutant PMP22, forming a stable complex called a dimer.
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Marilynn Martinson
Edina – Marilynn J. Martinson, 85, of Edina passed away peacefully Jan. 6, 2021 at Mount Olivet Care Center.
Private services were held Thursday Jan, 14 at Washburn McReavy funeral home in Edina, burial followed at Fort Snelling National Cemetery.
Marilynn Janet Anderson was born in Frost. She was baptized and confirmed at United Lutheran Church in Frost. She graduated from Frost High School and attended Gustavus Adolphus College. She married Robert E. Martinson and the couple resided most of their lives in Edina.
Marilynn’s foremost joy was being a wife, mother, and grandmother. Her professional life was spent working as an executive secretary. Along with this, she spent many years supporting Bob in his home building business, with an amazing eye for Interior Design. Marilynn enjoyed watching all sports, especially cheering on the Minnesota Vikings. She loved her family and granddaughters, entertaining them with jokes, limericks and rhymes, and was proud