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 E-Mail IMAGE: Mixscape separates a mixture of cells into perturbed (yellow) and non-perturbed ( escaping, grey) cells. view more  Credit: New York University/New York Genome Center A team of researchers from New York University and the New York Genome Center has developed a new computational tool to help understand the function and regulation of human genes. The results, published today in the journal Nature Genetics, demonstrate how to interpret experiments that combine the use of CRISPR to perturb genes along with multimodal single-cell sequencing technologies. The article describes how the new approach, called mixscape, helped to identify a new molecular mechanism for the regulation of immune checkpoint proteins that govern the immune system s ability to identify and destroy cancer cells.

New yorkUnited statesNew york universityEfthymia papalexiRahul satijaYork genome centerNational institutes of healthYork universityChan zuckerberg initiativeNew york genome centerNature geneticsSystems biologyNew york genomeNational institutesபுதியது யார்க்ஒன்றுபட்டது மாநிலங்களில்