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Researchers create new CRISPR tools to help contain mosquito disease transmission

UC San Diego scientists have developed a genetics toolkit that helps pave the way to a gene drive designed to stop Culex mosquitoes from spreading disease. Much less studied than other genera, Culex mosquitoes spread devastating afflictions stemming from West Nile virus, Japanese encephalitis virus and the pathogen causing avian malaria.

Noted Researcher and Scientific Leader Jack E Dixon Retires

Noted Researcher and Scientific Leader Jack E. Dixon Retires In a career spanning almost half-a-century, Dixon pioneered new discoveries and advanced science at both UC San Diego and the Howard Hughes Medical Institute Jack E. Dixon, PhD, whose distinguished and varied 48-year career ranged from helping reveal how cells communicate and fundamental processes of disease to becoming a renowned scientific leader, including terms as associate vice chancellor of scientific affairs at UC San Diego School of Medicine and as chief scientific officer at Howard Hughes Medical Institute, is retiring.  Jack Dixon, PhD, a renowned scientific leader at UC San Diego School of Medicine and Howard Hughes Medical Institute, is retiring after a distinguished 48-year career.

Study sheds new light on complex dynamics involved in microbial infections

Study sheds new light on complex dynamics involved in microbial infections Included in the vast fallout stemming from the COVID-19 pandemic, scientists are paying closer attention to microbial infections and how life forms defend against attacks from pathogens. Research led by University of California San Diego scientists has shed new light on the complex dynamics involved in how organisms sense that an infection is taking place. UC San Diego Assistant Project Scientist Eillen Tecle in Professor Emily Troemel s laboratory (Division of Biological Sciences) led research focusing on how cells that are not part of the conventional immune system respond to infections when pathogens attack. Scientists have conducted extensive research on so-called professional immune cells that are defensive specialists. Much less is known about how non-professional cells handle such threats.

Research uncovers how non-professional cells can trigger immune response

Researchers are finding new details on the complex dynamics involved in how organisms sense an infection from pathogens. The researchers found that worms can sense changes in their metabolism in order to unleash protective defenses, even if they don t directly sense an incursion from pathogens.

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