UMass team identifies cancer research breakthrough
Updated May 06, 2021;
Posted May 06, 2021
The University of Massachusetts Amherst Institute for Applied Life Sciences has been a home for research into the treatment of cancer and other diseases, where scientists say they are making a breakthrough. (JIM KINNEY/ THE REPUBLICAN)
Facebook Share
A team of University of Massachusetts Amherst researchers has announced the engineering of a tiny particle it says has the potential to revolutionize disease treatment, including for cancer.
The new research combines two different approaches to more precisely and effectively deliver treatment to the specific cells affected by cancer. The work has been ongoing at the UMass Amherst Institute for Applied Life Sciences, where researchers say a nanoparticle has far-reaching potential.
FINDINGS
A new study by researchers at the UCLA Jonsson Comprehensive Cancer Center has identified a novel combination therapy to potentially help overcome resistance to immunotherapy in people diagnosed with advanced lung cancer. The combination approach uses immune checkpoint inhibitors with ATRA, a safe medication that is widely used to treat leukemia. The team found the combination therapy led to eradication of over 70% of tumors when tested in mice with LKB1-deficient lung cancer. It also generated durable tumor-specific immunity.
BACKGROUND
Immune checkpoint inhibitors have substantially improved the outcomes for people with lung cancer. The five-year survival rate for patients with advanced disease on this therapy is more than 13% compared to 5% in patients with conventional chemotherapy. Although immunotherapy has been successful for many patients, a majority of patients still do not respond to the therapy.
中国空间站，一步步走来 - 看点 - 华声在线 voc.com.cn - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from voc.com.cn Daily Mail and Mail on Sunday newspapers.
罗强赴绵阳市调研文化旅游和教育事业发展工作_绵阳新闻网 myrb.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from myrb.net Daily Mail and Mail on Sunday newspapers.