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Subgingival periodontal dysbiosis was linked to markers of amyloid beta, but not tau, in cognitively normal older adults.
(Alzheimer s and Dementia: Diagnosis, Assessment, and Disease Monitoring)
(Brain)
Markers of inflammation in cerebrospinal fluid showed distinct patterns in frontotemporal dementia and in early and established Alzheimer s disease.
(Journal of Alzheimer s Disease)
The phase II KINETIC study of SAGE-324 led to a significant reduction in upper-limb tremor severity compared with placebo in adults with essential tremor, Sage Therapeutics and Biogen said, but trial participants experienced somnolence and dizziness.
Akili Interactive will work with Weill Cornell Medicine/NewYork-Presbyterian Hospital and Vanderbilt University Medical Center to evaluate a therapeutic video game to improve attention in people with COVID brain fog.
Washington [US], April 12 (ANI): Older adults with more harmful than healthy bacteria in their gums are more likely to have evidence for amyloid-beta, a key biomarker for Alzheimer's disease in their cerebrospinal fluid, according to new research by the New York University. However, this imbalance in oral bacteria was not associated with another Alzheimer's biomarker called tau.
Imbalanced bacterial community in the gums linked to Alzheimer s disease biomarker
Older adults with more harmful than healthy bacteria in their gums are more likely to have evidence for amyloid beta a key biomarker for Alzheimer s disease in their cerebrospinal fluid (CSF), according to new research from NYU College of Dentistry and Weill Cornell Medicine. However, this imbalance in oral bacteria was not associated with another Alzheimer s biomarker called tau.
The study, published in the journal
Alzheimer s & Dementia: Diagnosis, Assessment & Disease Monitoring, adds to the growing evidence of a connection between periodontal disease (gum disease) and Alzheimer s. Periodontal disease which affects 70 percent of adults 65 and older, according to CDC estimates is characterized by chronic and systemic inflammation, with pockets between the teeth and gums enlarging and harboring bacteria.
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Older adults with more harmful than healthy bacteria in their gums are more likely to have evidence for amyloid beta a key biomarker for Alzheimer s disease in their cerebrospinal fluid (CSF), according to new research from NYU College of Dentistry and Weill Cornell Medicine. However, this imbalance in oral bacteria was not associated with another Alzheimer s biomarker called tau.
The study, published in the journal
Alzheimer s & Dementia: Diagnosis, Assessment & Disease Monitoring, adds to the growing evidence of a connection between periodontal disease (gum disease) and Alzheimer s. Periodontal disease which affects 70 percent of adults 65 and older, according to CDC estimates is characterized by chronic and systemic inflammation, with pockets between the teeth and gums enlarging and harboring bacteria.