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The Nikkei share average ended 0.35 per cent lower at 28,860.80, while the broader Topix was down 0.28 per cent at 1,957.14.
AP
The Topix s sea transport subsector was the biggest decliner, sliding 3.33 per cent, following its surge to the highest in more than a decade.
TOKYO: Japanese equities closed lower on Wednesday, on profit-booking in shippers and semiconductor stocks, with investors awaiting US inflation data as it could influence how soon the Federal Reserve pares its stimulus programme. Financial firms and insurers declined after a retreat in long-term US Treasury yields dampened the outlook for returns on their portfolios. Eisai Co, however, surged 16.26 per cent, rising by the daily limit for a second straight session after its Alzheimer s drug received a nod from US regulators on Monday.
SYDNEY: Asian shares turned lower on Monday as relief over the benign U.S. jobs report was chilled by caution ahead of key inflation data later this week, while a coronavirus outbreak in Taiwan took a toll on chip manufacturers.