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As India eyes Sputnik rollout, experts question efficacy data

As India eyes Sputnik rollout, experts question efficacy data SECTIONS Share Synopsis The experts expressed concern regarding the availability of the data from which the Sputnik investigators drew their conclusions as they had refused to share it. A medical specialist holds a vial of Sputnik V vaccine against the coronavirus in a department store in Moscow. Picture credit: ( Reuters ) (This story originally appeared in on May 14, 2021)HYDERABAD: Even as India is gearing up to roll out Russian Covid-19 vaccine Sputnik V next week, a group of international experts has raised serious questions about the data discrepancies and substandard reporting of interim data of the vaccine’s phase 3 trials. Raising the red flag on discrepancies in the trials data, changes in the trial protocols, quality and accuracy of data as well as a lack of transparency, they said: “Restricted access to data hampers trust in research. Access to data underpinning study findings is imperative to che

Nerve stimulation reduces pain and opioid use after orthopedic surgery

 E-Mail A technique called percutaneous peripheral nerve stimulation yields impressive reductions in pain scores and opioid use during the first week after common orthopedic surgery procedures, concludes a randomized clinical trial published Online First in Anesthesiology, the official peer-reviewed journal of the American Society of Anesthesiologists (ASA), today. The benefits of postoperative nerve stimulation were much greater than what we had anticipated, concurrently reducing pain scores by more than 50 percent and opioid consumption by 80 percent, according to the randomized trial report by Brian M. Ilfeld, M.D., MS, and colleagues. With further study, they believe that peripheral nerve stimulation could be a safe, effective, opioid reducing, non-drug adjunct for pain management after surgery.

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