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email article Brain metastases are one of the most common and difficult-to-treat occurrences in metastatic breast cancer. They are found in 10% to 30% of patients. In patients with HER2-positive breast cancer, the rate of brain metastases is even higher up to 50%. Initial treatments for brain metastases include locally directed therapy with surgical resection, stereotactic radiosurgery, and/or whole-brain radiation therapy. Unfortunately, the rate of intracranial progression with these therapies is high. Even more problematic, most systemic therapies have limited efficacy due to their inability to pass through the blood-brain barrier. As patients live longer, they remain at risk for additional episodes of CNS [central nervous system] progression and/or new CNS metastases, Nancy Lin, MD, of the Dana-Farber Cancer Institute in Boston, told

United statesSan antonioDana farber cancer instituteNancy linEric winerAntonio breast cancerஒன்றுபட்டது மாநிலங்களில்சான் அன்டோனியோடானா ஃபார்‌பர் புற்றுநோய் நிறுவனம்நான்சி லின்அன்டோனியோ மார்பக புற்றுநோய்