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 E-Mail BOSTON - Immune checkpoint inhibitors, which boost the immune system s response against tumor cells, have transformed treatment for many advanced cancers, but short-term clinical trials and small observational studies have linked the medications with various side effects, most commonly involving the skin. A more comprehensive, population-level analysis now provides a thorough look at the extent of these side effects and provides insights on which patients may be more likely to experience them. The research was led by investigators at Massachusetts General Hospital (MGH) and is published in the Immunotherapies, which include immune checkpoint inhibitors, are an increasingly common treatment modality for advanced cancers, with more than 200,000 patients being started on these therapies annually, says co-senior author Yevgeniy R. Semenov, MD, an investigator in the Department of Dermatology at MGH. As the use of immune checkpoint inhibitors increases, so will the incidenc

United statesMark kalinichWilliam murphyVartan pahalyantsShannon wongvibulsinKerryl reynoldsFeicheng wangYevgeniyr semenovStevent chenKun hsing yuShawng kwatraNational institutes of healthDepartment of dermatologyJournal of the american academy dermatologyMassachusetts general hospitalAmerican academy