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Structural biology provides long-sought solution to innate immunity puzzle
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UT Southwestern scientists closing in on map of the mammalian immune system
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Nonagen Therapeutics Adds Drs. Bruce Beutler and Robert Kerbel to Scientific Advisory Board
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Nobel Laureate Joins Nonagen s Board
This is an exciting time for Nonagen, as we make our initial push to bring our best in class therapeutics to the clinic. LOS ANGELES (PRWEB) May 21, 2021 Today, Nonagen Therapeutics is delighted to welcome Drs. Bruce Beutler and Robert Kerbel to our Scientific Advisory Board (SAB). Dr. Beutler, Regental Professor and Director of the Center for Genetics of Host Defense at the University of Texas Southwestern Medical Center was the recipient of the 2011 Nobel Prize in Physiology and Medicine for his pioneering work on the innate immune system, including the discovery of TNF alpha, MIP1 alpha, MIP1 beta and others. Dr. Kerbel, Professor, University of Toronto, Canada Research Chair in Tumor Biology, Angiogenesis and Anti-Angiogenic Therapy, Canadian Institutes of Health Rese
Forward genetics used to identify gene linked to autism spectrum disorder
UT Southwestern scientists have adapted a classic research technique called forward genetics to identify new genes involved in autism spectrum disorder (ASD). In a study published this week in
eLife, the researchers used this approach in mice to find one such gene called KDM5A.
Approximately 1 in 54 children in the U.S. is diagnosed with ASD, a neurodevelopmental disorder that causes disrupted communication, difficulties with social skills, and repetitive behaviors. As a disease with a strong genetic component, it is hypothesized that thousands of genetic mutations may contribute to ASD. But to date, only about 30 percent of cases can be explained by known genetic mutations.
Credit: Photo taken by Brian Coats for UT Southwestern Medical Center
DALLAS - Dec. 22, 2020 - UT Southwestern scientists have adapted a classic research technique called forward genetics to identify new genes involved in autism spectrum disorder (ASD). In a study published this week in
eLife, the researchers used this approach in mice to find one such gene called KDM5A.
Approximately 1 in 54 children in the U.S. is diagnosed with ASD, a neurodevelopmental disorder that causes disrupted communication, difficulties with social skills, and repetitive behaviors. As a disease with a strong genetic component, it is hypothesized that thousands of genetic mutations may contribute to ASD. But to date, only about 30 percent of cases can be explained by known genetic mutations.
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