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Stem cells reproduce beginnings of placenta

Kyoto University Naïve and primed PSCs (iPS cells and embryonic stem cells) represent different periods in development (before and after the embryo implants itself into the uterus). Naïve PSCs can become all the major cell components that make up the villi, which goes on to become the placenta. Primed PSCs cannot and instead form cells that lead to the amnion. The Yasuhiro Takashima lab shows that naïve iPS cells can be induced to form all the stages that mimic early placenta development in humans. Gynecologist Shingo Io knows that during birth there will not only be a baby leaving the mother’s body. Joining the cries that bring joy to the room will be a silent entity, the placenta. Like the baby, this tissue only began to grow upon conception, but little is known about how the placenta develops inside the mother. A new study by Io, CiRA Junior Associate Professor Yasuhiro Takashima and colleagues reports how iPS cells can be used to study this development. The

Rise in pregnant women and babies suffering amid pandemic

Pregnant women and their babies are suffering worse outcomes during the pandemic, and researchers are sounding the alarm for immediate action to avoid rolling back decades of global investment in safe maternity care. Data from an analysis of 40 studies published during the last year across 17 countries found rates of stillbirth and maternal mortality increased by a third. Outcomes were worse in low- and middle-income countries, according to a report in The Lancet medical journal. The increases may be driven by the pressure Covid-19 put on health systems rather than measures aimed at limiting the spread of the virus, such as lockdowns, the researchers said. Studies from individual countries suggested pregnant woman reduced their care-seeking because of the fear of infection, as well as reduced provision of maternity services.

Covid-19: Pregnant women, babies suffering worse outcomes during pandemic

The outcomes represent a reversal of recent progress toward making pregnancy safer for mothers and children worldwide, said Andreea Creanga, physician and associate professor in the Department of International Health and Department of Gynecology and Obstetrics at Johns Hopkins University. The world had made progress in ensuring antenatal care and deliveries in health facilities staffed by health workers, and the focus had shifted in recent years to increasing the quality of the care that women and babies received. Difficult road “Now, we are going to go back and make sure that women come to facilities to get the care they need for themselves and for their infants,” she said. “It’s a difficult road ahead.”

As escolhas da mulher moderna e a fertilidade

As escolhas da mulher moderna e a fertilidade
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