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Developments in the Quality Assurance for Concrete Pavement Mix Design Using Petrography and Fluorescence Microscopy

Chunyu Qiao and DRP, a Twining Company The construction of concrete pavements can see unexpected events that require contractors to verify the quality and durability of the in-place concrete. Such events include exposure to rain during placement, late applications of curing compounds, plastic shrinkage cracking hours within hours of the placement, and problems texturing and curing the concrete. Even when strength requirements and other material tests are satisfied, engineers may call for the removal and replacement of sections of pavement over concerns regarding the compliance of in-place material with mix design specifications. In such cases, petrography and other complementary (but specialized) test methods can provide important information on the quality and durability of concrete mixtures and their compliance with job specifications.

Researchers discover specific blood biomarker that predicts kidney transplant rejection

Researchers discover specific blood biomarker that predicts kidney transplant rejection Researchers at the University of Pittsburgh School of Medicine have discovered a blood biomarker that predicts kidney transplant rejection with a lead time of about eight months, which could give doctors an opportunity to intervene and prevent permanent damage. These results, published today in Science Translational Medicine, not only identify a warning signal that something is going wrong, but also suggest an existing medication that could be given to these patients to right the course of their long-term recovery. We can t tell a priori if a patient is on too much or too little immune suppression-;we don t know until after rejection or an infection has already started. We wanted to find something that would tell us this patient is at risk of rejecting later so that we could change their immunosuppressants up front before the immune system revs up, before scarring and chronic damage is done

Blood Test for Kidney Rejection Suggests New Treatment

Date Time Blood Test for Kidney Rejection Suggests New Treatment PITTSBURGH– Researchers at the University of Pittsburgh School of Medicine have discovered a blood biomarker that predicts kidney transplant rejection with a lead time of about eight months, which could give doctors an opportunity to intervene and prevent permanent damage. These results, published today in Science Translational Medicine, not only identify a warning signal that something is going wrong, but also suggest an existing medication that could be given to these patients to right the course of their long-term recovery. “We can’t tell a priori if a patient is on too much or too little immune suppression we don’t know until after rejection or an infection has already started,” said senior author David Rothstein, M.D., the Pittsburgh Steelers Chair in Transplantation and professor of surgery, medicine and immunology at Pitt. “We wanted to find something that would tell us this patient is at risk of

Blood test for kidney rejection suggests new way to treat post-transplant patients

 E-Mail IMAGE: Pittsburgh Steelers Chair in Transplantation and professor of surgery, medicine and immunology, University of Pittsburgh School of Medicine view more  Credit: Thomas E. Starzl Transplantation Institute at the University of Pittsburgh PITTSBURGH, Feb. 24, 2021 - Researchers at the University of Pittsburgh School of Medicine have discovered a blood biomarker that predicts kidney transplant rejection with a lead time of about eight months, which could give doctors an opportunity to intervene and prevent permanent damage. These results, published today in Science Translational Medicine, not only identify a warning signal that something is going wrong, but also suggest an existing medication that could be given to these patients to right the course of their long-term recovery.

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