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Fixing genetic mistakes to restore vision For news media
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Using a new approach to target genetic mutations, eye researchers at the University of Wisconsin–Madison and University of Iowa are developing and testing a new therapy for restoring vision in children and adults with severe visual impairment or blindness due to certain kinds of retinal disorders.
Bikash Pattnaik
“For pediatric populations, this new therapy will be tested to treat inherited retinal disorders like Leber congenital amaurosis, Best disease, or more frequent congenital stationary night blindness,” says Bikash Pattnaik, UW–Madison professor of pediatrics and ophthalmology and visual sciences at the McPherson Eye Research Institute and the School of Medicine and Public Health.
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UW-Madison leads DoD-funded effort to restore vision to injured soldiers and people with disease
Human pluripotent stem cell-derived photoreceptors (cell bodies labeled in red, nuclei labeled in blue) grown on a biodegradable scaffold. Image courtesy of Allison Ludwig, Gamm Lab
A team of researchers led by University of Wisconsin-Madison professor David Gamm is developing a transplantable retinal patch intended to help restore vision to military personnel blinded in the line of duty and to treat individuals with degenerative eye diseases such as macular degeneration.
The technology, funded by a U.S. Department of Defense grant exceeding $5 million, will be based on a system in which human induced pluripotent cells are used to generate light-responsive eye cells called photoreceptors along with the cells that support them, called retinal pigment epithelium.
UWâMadison leads DoD-funded effort to restore vision to injured service members and people with disease For news media
More information
Human pluripotent stem cell-derived photoreceptors (cell bodies labeled in red, nuclei labeled in blue) grown on a biodegradable scaffold. Image courtesy of Allison Ludwig, Gamm Lab
A team of researchers led by University of WisconsinâMadison professor David Gamm is developing a transplantable retinal patch intended to help restore vision to military personnel blinded in the line of duty and to treat individuals with degenerative eye diseases such as macular degeneration.
The technology, funded by a U.S. Department of Defense grant exceeding $5 million, will be based on a system in which human induced pluripotent cells are used to generate light-responsive eye cells called photoreceptors along with the cells that support them, called retinal pigment epithelium.