Published: Apr 28, 2021
Neuronal viability was preserved, resulting in improved spatial learning and memory
GAITHERSBURG, Md. (BUSINESS WIRE) Neuraly, a clinical stage biotechnology company pioneering disease-modifying agents for neurodegenerative disorders, today announced publication in the peer-reviewed journal
Acta Neuropathologica Communications of preclinical data that contributed to the therapeutic rationale for clinical evaluation of NLY01 in Alzheimer’s and Parkinson’s diseases. The research was conducted in collaboration with Dr. Ted Dawson’s lab at the Johns Hopkins School of Medicine.
The publication, entitled “Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer’s disease” demonstrated that NLY01, an engineered exendin-4, glucagon-like peptide-1 receptor (GLP-1R) agonist, can selectively block β-amyloid-induced activation of microglia through upregulated GLP-1R, inhibit formation of reactive astro
Jakob Helbig/Getty Images
Homebuyers have flocked to the Rocky Mountains in droves since the onset of the pandemic.
Luxury real-estate sales have gone through the (ski chalet) roof in markets like Aspen, Vail, and Jackson Hole.
In 2020, a top Jackson Hole broker saw sales volume increase by more than 300% increase.
As Americans fled major cities in 2020, New York s and San Francisco s losses were the Rocky Mountains gain.
Colorado emerged last summer as a draw for wealthy Americans and rootless millennials amid the pandemic, but it s the region s elite ski towns that stand at the center of a red-hot residential market.
Real estate sales in Jackson Hole soared in 2020, and the agents involved in the record market say it was the disaster of COVID-19 and everything that came with it that created the rush to sell and buy.
Jackson Hole Real Estate Associates, the Christieâs affiliate here, said total sales in the area hit $2.35 billion, up 90% over 2019, with hot residential sales accounting for $1.58 billion of that. Christieâs counted 847 transactions.
Another local standard, the Jackson Hole Report compiled by David Viehman of Engel&Volkers, put total sales at $2.45 billion and 878 transactions. Viehman counted 402 single-family house sales with a total price of $1.49 billion, up 52%. He noted another 263 condo and townhouse sales for $384 million, that dollar amount a 49% rise.
Share or Print this page
In aggressive pursuit of its vision of a world without Alzheimer’s and all other dementia, the Association once again made its
largest-ever research investment in FY20,
granting more than $47 million to 139 new scientific investigations. Investments included awards to 119 projects funded through the
International Research Grant Program, representing proposals ranked highest by a peer-reviewed process in a highly competitive field of 406 applications submitted from 865 letters of intent. As the world’s leading nonprofit funder of Alzheimer’s and dementia research, the Association is currently investing $208 million in more than 590 active best-of-field projects in 31 countries.
The Association paused funding programs in March 2020 after hearing significant challenges from potential applicants in submitting their necessary documents for consideration as a result of the COVID-19 pandemic. The Association continues to be in touch with multi