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Add-On PI3K Inhibitor Wins in Relapsed, Indolent NHL

email article Adding the PI3K inhibitor copanlisib (Aliqopa) to rituximab reduced the risk of disease progression or death for patients with relapsed indolent non-Hodgkin s lymphoma (NHL), including those unfit for chemotherapy, a phase III trial called CHRONOS-3 showed. Among more than 450 patients receiving rituximab, the median progression-free survival (PFS) reached 21.5 months with copanlisib, as compared to 13.8 months for those assigned placebo (HR 0.52, 95% CI 0.39-0.69, P

Personalized Cancer Vaccine Guided by Mount Sinai Computations Is Safe, Shows Potential Benefit Against Multiple Tumor Types

Personalized Cancer Vaccine Guided by Mount Sinai Computations Is Safe, Shows Potential Benefit Against Multiple Tumor Types Share Article A personalized cancer vaccine developed with the help of a Mount Sinai computational platform raised no safety concerns and showed potential benefit in patients with different cancers, including lung and bladder, that have a high risk of recurrence, according to results from an investigator-initiated phase I clinical trial presented during the virtual American Association for Cancer Research (AACR) Annual Meeting 2021, held April 10-15. NEW YORK (PRWEB) April 10, 2021 A personalized cancer vaccine developed with the help of a Mount Sinai computational platform raised no safety concerns and showed potential benefit in patients with different cancers, including lung and bladder, that have a high risk of recurrence, according to results from an investigator-initiated phase I clin

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