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Metal-based molecule inhibits the build-up of Alzheimer s peptides in lab tests In lab tests, Imperial researchers have created a metal-based molecule that inhibits the build-up of a peptide associated with Alzheimer s disease. A peptide is a fragment of a protein, and one of the key hallmarks of Alzheimer s disease is the build-up of a specific peptide known as amyloid-β. The team demonstrated that with the aid of ultrasound, their molecule can cross the blood-brain barrier in mice, targeting the part of the brain where the damaging peptide most often accumulates. Alzheimer s disease is the most common form of dementia, affecting approximately 50 million people worldwide. There is a pressing need to develop drugs that can prevent or reverse the effects of this devastating disease.

City ofUnited kingdomTiffany chanRamon vilarEmily hendersonDepartment of chemistry at imperialImperial college londonFirst authorImperial collegeProfessor ramon vilarநகரம் ஆஃப்ஒன்றுபட்டது கிஂக்டம்டிஃப்பனி சான்ராமன் விலார்எமிலி ஹென்டர்சன்துறை ஆஃப் வேதியியல் இல் ஏகாதிபத்தியம்