A dog’s nose could hold the key to detecting the most lethal type of prostate cancer, scientists have said.
Results from a study involving Milton Keynes-based charity Medical Detection Dogs could lead to the development of a more sensitive and specific prostate cancer diagnostic method beyond the blood test which is currently used, researchers said.
They hope the work can be replicated in a bigger study and eventually result in the production of a “robotic nose” perhaps in the form of a smartphone app.
Florin the Labrador sniffs urine samples (Medical Detection Dogs/PA)
Dr Claire Guest, co-founder and chief scientific officer of Medical Detection Dogs, said the publication of the study is “extremely exciting”.
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A 4-year-old Labrador and a 7-year-old Vizsla were trained to detect the odor of prostate cancer in urine samples collected from patients with the disease, including Gleason 9 prostate cancer the most lethal tumors that would benefit the most from early detection.
Results showed the dogs correctly identified positive samples 71% of the time, and correctly ignored negative samples including those with other diseases 70% to 76% of the time. The dogs also correctly identified when 73% of blinded patient samples did not have the disease, which compares favorably to the most commonly used prostate cancer test, the PSA blood test. This study showed that a dog s nose could hold the key to an urgently needed, more accurate, and non-invasive method of early prostate cancer diagnosis, said Claire Guest of Medical Detection Dogs, lead author of the study. …. This has enormous potential and in time the ability of the dogs nose could be translated to an electronic device.
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