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Study identifies protein that appears to prevent tumour cells from spreading

Study identifies protein that appears to prevent tumour cells from spreading
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United statesKonstantinos konstantopoulosKaustav beraUniversitat pompeu fabraChristopher yankaskasUniversity of albertaJohns hopkins kimmel cancer centerJohns hopkins university phScience advancesJohns hopkins university phdUniversitat pompeuJohns hopkins kimmel cancerThermo fisherஒன்றுபட்டது மாநிலங்களில்பல்கலைக்கழகம் ஆஃப் ஆல்பர்ட்டாஜான்ஸ் ஹாப்கின்ஸ் கீம்மேல் புற்றுநோய் மையம்

Science News | Study Identifies Protein That Appears to Prevent Tumour Cells from Spreading

Science News | Study Identifies Protein That Appears to Prevent Tumour Cells from Spreading
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Field of mathematics reveals a potential gene that causes acute lymphoblastic leukemia

Field of mathematics reveals a potential gene that causes acute lymphoblastic leukemia
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United statesAndrew feinbergJohn goutsiasMichael koldobskiyJohns hopkinsEmily hendersonJohns hopkins universityWhiting school of engineeringBloomberg school of public healthJohns hopkins kimmel cancer centerDepartment of electricalJohns hopkins university school of medicineJohns hopkins medicineBloomberg distinguished professorJohns hopkins university schoolWhiting school

Information theory recruited to help scientists find cancer genes

Information theory recruited to help scientists find cancer genes
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United statesBaylor college of medicinePatrick brownWeiqiang zhouColin callahanElisabet pujadasGarrett jenkinsonVarenka rodriguez diblasiJohns hopkinsChallice bonifantAdrian idriziRakel tryggvadottirAndrew feinbergJordi abanteMichael koldobskiyJohn goutsias

New cancer immunotherapy uses engineered T cells to target a common genetic alteration

New cancer immunotherapy uses engineered T cells to target a common genetic alteration Researchers developed a prototype for a new cancer immunotherapy that uses engineered T cells to target a genetic alteration common among all cancers. The approach, which stimulates an immune response against cells that are missing one gene copy, called loss of heterozygosity (LOH), was developed by researchers at the Ludwig Center, Lustgarten Laboratory and the Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center. Genes have two alleles, or copies, with one copy inherited from each parent. Cancer-related genetic alterations commonly involve the loss of one of these gene copies.

Kenneth kinzlerShibin zhouMichael hwangBert vogelsteinEmily hendersonLudwig centerBloomberg kimmel institute for cancer immunotherapyJohns hopkins kimmel cancer centerProceedings of the national academy sciencesJohns hopkins university school of medicineLustgarten laboratoryKimmel instituteJohns hopkins kimmel cancerNational academyJohns hopkins university schoolBrian mog