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Noninvasive brain stimulation restores behavioral flexibility in cocaine-exposed rats A major impediment to treatment of substance use disorder (SUD) is a loss of behavioral flexibility, whereby one s judgment is impaired such that their actions continuously result in negative consequences. Such decisions include continuing to use drugs, but this inflexibility extends to other areas of life and can continue even well into abstinence from drug use. Previous research in animals suggests that this inflexibility can be traced to reduced neural signaling in brain regions critical for behavioral flexibility. Now, a new study led by Elizabeth West, PhD, and Regina Carelli, PhD, of the Carolina Center for Neurostimulation, University of North Carolina, Chapel Hill, NC, USA, shows that a noninvasive form of brain stimulation used in cocaine-exposed rats kick-started the brain activity and restored behavioral flexibility in the rodents. The paper appears in

United statesRegina carelliJohn krystalEmily hendersonCarolina centerUniversity of north carolinaElizabeth westNorth carolinaChapel hillBiological psychiatryBrain stimulationSubstance use disorderஒன்றுபட்டது மாநிலங்களில்ரெஜினா காரெல்லிஜான் கிரிஸ்டல்எமிலி ஹென்டர்சன்