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An Overview of Morphogens and their Signaling Pathway Morphogens are signaling molecules that are released from particular areas of tissues, creating a concentration gradient that decreases in concentration further away from the source. This has implications for development, where cell and tissue differentiation is linked to the concentration of morphogens in the environment. In one study, genetic mutations linked to congenital heart defects were shown to elevate the signaling of the Hedgehog morphogen family in mice, which then led to heart defects. Bone morphogenetic protein 7 (BMP-7) is a morphogen that plays an important role in development of bone and cartilage. Image Credit: StudioMolekuul / Shutterstock.com

Studiomolekuul shutterstockHeart development developmental cellNature reviews molecular cell biologyHedgehog signalingSonic hedgehogஇதயம் வளர்ச்சி வளர்ச்சி செல்இயற்கை மதிப்புரைகள் மூலக்கூறு செல் உயிரியல்முள்ளம்பன்றி சமிக்ஞைசோனிக் முள்ளம்பன்றி