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What We Know About SARS-CoV-2 One Year Later: Part 2
Sponsored Content by ACROBiosystemsApr 14 2021
The S protein of SARS-CoV had been studied extensively before the SARS-CoV-2 outbreak. Among other structural proteins of SARS-CoV-2, the S protein was discovered to be highly immunogenic and effective at neutralizing antibodies recovered from SARS patients were directed at S protein.
6,7
Research into therapeutics and vaccines against SARS-CoV-2 was focused immediately on the S protein. Although the four structural proteins of the novel SARS-CoV share over 90% in sequence identity with SARS-CoV-2, S protein consisting of S1 and S2 subunits diverged had just 77% sequence similarity.
1
The S1 subunit contains the NTD or the N-terminal domain and Receptor binding domain (RBD), which binds to the human angiotensin-converting enzyme-2 (ACE2) mainly through direct interaction with the receptor-binding motif (RBM).
In this first in a series of four articles, ACROBiosystems review what they know about SARS-CoV-2 and COVID-19, the developments in fighting the pandemic and the threat of emerging variants.
What We Know About SARS-CoV-2 One Year Later: Part 4 news-medical.net - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from news-medical.net Daily Mail and Mail on Sunday newspapers.
Kent Variant News | Live Feed&Top Stories newsnow.co.uk - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from newsnow.co.uk Daily Mail and Mail on Sunday newspapers.