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Mechanisms of many human chronic diseases involve abnormal action of the immune system and/or altered metabolism. The microbiome, an important regulator of metabolic and immune-related phenotypes, has been shown to be associated with or participate in the development of a variety of chronic diseases. Viruses of bacteria (i.e., “phages”) are ubiquitous and mysterious, and several studies have shown that phages exert great control over the behavior and misbehavior of their host bacteria. This study uses techniques to discover and analyze over 45,000 viruses associated with human bodies. The abundance of over 2,000 specific phages is found to correlate with a variety of common chronic diseases. Fasta sequence files from CHVD databases can be accessed at (<https://zenodo.org/record/4498884>) ([56][1]). Additionally, all unique virus genomes with metadata and annotated genome maps have been deposited to GenBank under BioProject [PRJNA573942][2]. Accession numbers for individual v

Nathan fonsGabriel starrettLinda frisseNational cancer instituteGenbank national centerNational library of medicineIntramural research programRed queenHuman viromeForest classifiersNational centerBiotechnology informationNational libraryNational cancerதேசிய புற்றுநோய் நிறுவனம்தேசிய நூலகம் ஆஃப் மருந்து