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Antiobiotics Tied to a 50 Percent Greater Risk of Colon Cancer

Drawing on a large primary care database of up to two million people in Scotland, researchers from the University of Aberdeen and Queen’s University Belfast looked at health records of nearly 8,000 people with colorectal cancer (sometimes referred to as bowel cancer). Annals of Oncology, showed that antibiotic use was linked with an increased risk of colon cancer across all ages. But the likelihood was almost 50 percent higher in those under age 50, compared with 9 percent higher in individuals over 50. “Junk food, sugary drinks, obesity, and alcohol are likely to have played a part in that rise [of colorectal cancer cases], but our data stress the importance of avoiding unnecessary antibiotics, especially in children and young adults,” said lead author Sarah Perrott, MBChB, of the School of Medicine at the University of Aberdeen, in a July 2 statement.

Antibiotic Link to Rise in Early Onset Colon Cancer?

Antibiotic Link to Rise in Early Onset Colon Cancer? By Liam Davenport July 12, 2021 Exposure to antibiotics appears to be associated with the development of colon cancer, particularly in younger people, and could be contributing to the increase in early onset colorectal cancer (CRC) that is being documented, say UK researchers. The team conducted study using data from primary care in Scotland, which involved almost 8,000 cases of CRC and over 30,000 healthy controls. The analysis suggests that a history of antibiotic use among individuals younger that 50 appeared to increase the risk of developing colon cancer (but not rectal) by 49%. To our knowledge, this is the first study to link antibiotic use with the growing risk of early onset colon cancer, a disease which has been increasing at a rate of at least 3% per year over the last two decades, said study presenter Sarah Perrott, a medical student at the University of Aberdeen, Scotland, U.K.

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