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Malene Hansen, PhD, and Morgan Levine, PhD, honored by AFAR, recognized with 2021 Irving S Wright Award and Vincent Cristofalo Rising Star Award

Malene Hansen, PhD, and Morgan Levine, PhD, honored by AFAR, recognized with 2021 Irving S Wright Award and Vincent Cristofalo Rising Star Award
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Tumor marker may help overcome endocrine treatment-resistant breast cancer

 E-Mail Credit: Sanford Burnham Prebys LA JOLLA, CALIF. - May 19, 2021 - A study led by scientists at Sanford Burnham Prebys Medical Discovery Institute has identified a tumor marker that may be used to predict which breast cancer patients will experience resistance to endocrine therapy. The research offers a new approach to selecting patients for therapy that targets HER2, a protein that promotes the growth of cancer cells, to help avoid disease relapse or progression of endocrine-sensitive disease. The study was published in the journal Nature Communications. Nearly 80% of breast tumors are estrogen receptor (ER)-positive. For decades, these tumors have been treated with anti-estrogen (endocrine) therapies to lower estrogen levels and help slow the cancer s growth. About 20% of breast cancers are also HER2-positive at diagnosis, and these tumors tend to be more aggressive and fast-growing, as HER2 is a receptor that when active, promotes the rapid growth of breast cancer cel

Frontline Cancer: Health systems unite in fight against cancer and cyber threats

I swear to fulfill, to the best of my ability and judgment, this covenant: I will respect the hard-won scientific gains of those physicians in whose steps I walk and gladly share such knowledge as is mine with those who are to follow. I will apply, for the benefit of the sick, all measures [that] are required. … I will not be ashamed to say “I know not,” nor will I fail to call in my colleagues when the skills of another are needed for a patient’s recovery. I will remember that I do not treat a fever chart, a cancerous growth, but a sick human being whose illness may affect the person’s family and economic stability. My responsibility includes these related problems, if I am to care adequately for the sick.

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