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WSG and CANKADO s EnReP predicts the benefits of anti-hormone therapy in breast cancer patients

The tool developed on the basis of the ADAPT study data will be presented today at SABCS 2020 Cologne, Germany, 11.12.2020 – The EnReP (Endocrine Response Predictor) assessment tool will be presented today at the San Antonio Breast Cancer Symposium SABCS 2020. EnReP is a tool developed in Germany that can be used to predict the probability of response to endocrine therapy in early-stage breast cancer patients. Endocrine therapy is the standard therapy for hormone receptor-positive (HR+) / HER2-negative (HER2-) breast cancer patients. The ADAPT study program evaluates options for patient-specific decision-making for breast cancer treatment based on modern biological markers. A central component here is the examination of the tumor’s response to a brief anti-hormone therapy prior to operation.

Online Tool Refines Individual Risks in Breast Cancer

email article SAN ANTONIO An online tool, which incorporates clinicopathological data and the results of the 21-gene recurrent score, was able to estimate risk of distant recurrence (DR) and adjuvant chemotherapy benefit in certain patients with breast cancer, a researcher reported. The RSClin tool integrates the recurrence score (RS) with tumor grade, tumor size, and age using a patient-specific meta-analysis that included 10,004 women with hormone receptor-positive, HER2-negative, and node-negative breast cancer who received endocrine therapy alone in the B-14 trial, or with chemotherapy in the TAILORx trial, explained Joseph Sparano, MD, of Montefiore Medical Center and the Albert Einstein College of Medicine in New York City, at the San Antonio Breast Cancer Symposium virtual meeting. The study was simultaneously published in the

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