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Non-invasive technology shows potential to overcome detrimental effects of aging and dementia

Non-invasive technology shows potential to overcome detrimental effects of aging and dementia Ultrasound can overcome some of the detrimental effects of aging and dementia without the need to cross the blood-brain barrier, Queensland Brain Institute researchers have found. Professor Jürgen Götz led a multidisciplinary team at QBI s Clem Jones Centre for Ageing Dementia Research who showed low-intensity ultrasound effectively restored cognition without opening the barrier in mice models. The findings provide a potential new avenue for the non-invasive technology and will help clinicians tailor medical treatments that consider an individual s disease progression and cognitive decline. Historically, we have been using ultrasound together with small gas-filled bubbles to open the almost-impenetrable blood-brain barrier and get therapeutics from the bloodstream into the brain, Professor Götz said.

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